BiophysicsbioRxiv
The C-terminal actin binding domain of talin forms an asymmetric catch bond with F-actin
L. M. Owen, N. A. Bax, W. Weis, A. R. Dunn
This study shows that the C-terminal actin binding domain of talin forms an asymmetric catch bond with F-actin under mechanical load, supporting a mechanism for focal adhesion formation.
DOI 10.1073/pnas.2109329119