MicrobiologybioRxivPreprint
Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerase (PARP), blocks replication of the SARS-CoV-2 human coronavirus in vitro.
N. E. Stone, S. A. Jaramillo, A. N. Jones…·C. T. French
This paper evaluates stenoparib, a PARP inhibitor, for antiviral activity against SARS-CoV-2 and other coronaviruses in vitro, showing dose-dependent suppression and potential synergy with remdesivir.
DOI 10.1101/2020.11.12.380394