ImmunologybioRxiv
Loss of FOXP3 function causes expansion of two pools of autoreactive T cells in patients with IPEX syndrome.
S. Borna, E. Lee, U. Lakshmanan…·R. Bacchetta
FOXP3 mutations in humans lead to expansion of autoreactive T cells from both effector and regulatory T cells that gain effector function.
DOI 10.1126/scitranslmed.adg6822