Author

L. Nierzwicki

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Biophysics· 1

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Approach:biophysical modeling· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

G. P. Lisi· 1 shared G. Palermo· 1 shared K. W. East· 1 shared P. R. Arantes· 1 shared U. N. Morzan· 1 shared V. S. Batista· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

G. P. Lisi

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1 paper

Recent·Most cited

BiophysicsbioRxivSep 14, 2021

Enhanced Specificity Mutations Perturb Allosteric Signaling in CRISPR-Cas9

G. Palermo, L. Nierzwicki, K. W. East…·V. S. Batista

The paper investigates how specificity-enhancing mutations in CRISPR-Cas9 affect allosteric signaling, showing that mutations like K855A disrupt the HNH domain structure and signaling transfer more than others.

DOI 10.7554/elife.73601

biophysical modelingprotein folding & dynamics

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