Cell BiologybioRxivPreprint
An mTOR-independent Macroautophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes
L. Yoon, R. C. Botham, A. Verhelle…·S. Encalada
The paper identifies CCT020312, an mTOR-independent autophagy activator, which reduces tauopathy and prionopathy neurodegeneration phenotypes by enhancing autophagy flux and clearing protein aggregates.
DOI 10.1101/2022.09.29.509997