DNA methylation and survival differences associated with the type of IDH mutation in 1p/19q non-codeleted astrocytomas
M. Tesileanu, W. Vallentgoed, M. Sanson, W. Taal, P. Clement, W. Wick, A. Brandes, J.-F. Baurain, O. Chinot, H. Wheeler, S. Gill, M. Griffin, L. Rogers, R. Ruda, M. Weller, , van den Bent
The paper shows that IDH mutations other than p.R132H in 1p/19q non-codeleted astrocytomas are linked to higher DNA methylation and better patient survival.
bioRxiv · Dec 10, 2020 · PreprintCancer Biology