S. Gill

Affective Symptoms in Pregnancy are Associated with the Vaginal Microbiome

This study links affective symptoms during pregnancy to vaginal microbiome composition, showing associations with specific taxa and metabolic pathways.

Enhanced delivery of protein therapeutics with a diphtheria toxin-like platform that evades pre-existing neutralizing immunity

This paper identifies a diphtheria toxin homolog from Austwickia chelonae that evades pre-existing anti-DT antibodies and shows improved cargo delivery compared to diphtheria toxin.

Glioblastoma induces the recruitment and differentiation of hybrid neutrophils from skull bone marrow

This study identifies hybrid neutrophils with dendritic features in glioblastoma that suppress tumor growth and originate from skull bone marrow.

Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations

This study identifies the transsulfuration pathway as a targetable metabolic driver of glioblastoma invasion through multi-omic analyses of engineered biomaterials and patient biopsies.

The Streptococcus mutans Rhamnose-glucose Polysaccharide Plays an Important Role in Oxidative Stress Resistance and Iron Homeostasis

This study shows that RGP in S. mutans affects iron homeostasis and oxidative stress resistance by altering iron uptake and increasing antioxidant gene expression.

DNA methylation and survival differences associated with the type of IDH mutation in 1p/19q non-codeleted astrocytomas

The paper shows that IDH mutations other than p.R132H in 1p/19q non-codeleted astrocytomas are linked to higher DNA methylation and better patient survival.

Characterization of chondroitinase-induced lumbar intervertebral disc degeneration in a sheep model intended for assessing biomaterials

This paper characterizes a sheep model of chondroitinase-induced intervertebral disc degeneration to evaluate biomaterials for disc repair.

Long-term associations and insights on social structure of the Humpback whales in Prince William Sound, Alaska

This study identifies two distinct social groups of humpback whales in Prince William Sound over 27 years, showing long-term associations that persist through migration.

Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor

This study evaluates deacetylase inhibitors in metaplastic breast carcinoma using multiple preclinical models, finding they reduce metastasis and synergize with chemotherapy.

Impaired tumor death receptor signaling drives resistance to CAR T cell therapy

This study identifies impaired death receptor signaling as a driver of resistance to CAR T cell therapy in B-cell leukemia by showing its role in tumor survival and T cell dysfunction.

Differential Effector Response of Amnion- and Adipose-Derived Mesenchymal Stem Cells to Inflammation; Implications for Intradiscal Therapy

This study compares the inflammatory response of amnion- and adipose-derived mesenchymal stem cells in intervertebral disc degeneration, finding AM-MSCs produce more anti-inflammatory cytokines and chondrogenic matrix while AD-MSCs proliferate more and produce pro-inflammatory cytokines.

Pesticide exposure affects flight dynamics and reduces flight endurance in bumblebees

This study shows that acute imidacloprid exposure reduces flight endurance and alters velocity in bumblebees, potentially impacting foraging and pollination.

Multi-laminate Annulus Fibrosus Repair Scaffold with an Interlamellar Matrix Enhances Impact Resistance, Prevents Herniation and Assists in Restoring Spinal Kinematics

This study enhances a collagen-based scaffold with a glycosaminoglycan interlamellar matrix to improve impact resistance, restore spinal kinematics, and prevent disc herniation.