Cancer BiologybioRxivPreprint
Adipose triglyceride lipase is regulated by CAMKK2-AMPK signaling and drives advanced prostate cancer
D. Awad, T. L. Pulliam, M. L. Spradlin…·D. E. Frigo
This study identifies ATGL as a CAMKK2-AMPK target that promotes CRPC progression by enhancing lipase activity and metabolic plasticity, suggesting it as a therapeutic target.
DOI 10.1101/2022.11.02.514910