Cancer BiologybioRxiv
8-azaadenosine and 8-chloroadenosine are not selective inhibitors of ADAR
K. A. Cottrell, L. S. Torres, J. D. Weber
This paper shows that 8-azaadenosine and 8-chloroadenosine are not selective ADAR inhibitors, as they affect ADAR-dependent and independent cell lines equally and do not activate PKR or alter A-to-I editing.
DOI 10.1158/2767-9764.crc-21-0027