Author

L. Scietti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

F. Forneris· 3 shared A. Pinnola· 2 shared S. Faravelli· 2 shared A. Chiapparino· 1 shared D. Mattoteia· 1 shared E. Criscuolo· 1 shared F. De Giorgi· 1 shared M. Castelli· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBiochemistry

F. Forneris

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular Structure and Enzymatic Mechanism of the Human Collagen Hydroxylysine Galactosyltransferase GLT25D1/COLGALT1

M. De Marco, S. R. Rai, L. Scietti, D. Mattoteia, S. Liberi, A. Pinnola, F. Forneris

This study characterizes the molecular structure and enzymatic mechanism of GLT25D1/COLGALT, identifying its catalytic site and dimeric assembly as critical for collagen lysine modification.

bioRxiv · Jun 21, 2024Biochemistry

SARS-CoV-2 Spike Affinity and Dynamics Exclude the Strict Requirement of an Intermediate Host

M. Castelli, L. Scietti, N. Clementi, M. Cavallaro, S. Faravelli, A. Pinnola, E. Criscuolo, R. A. Diotti, M. Clementi, F. Forneris, N. Mancini

This study shows SARS-CoV-2 and RaTG13 spikes have similar ACE2 binding affinities, suggesting minimal species barriers, and highlights SARS-CoV-2's optimized dynamics for human ACE2 engagement.

bioRxiv · Aug 11, 2021 · PreprintMicrobiology

A cooperative network of molecular "hot spots" highlights the complexity of LH3 collagen glycosyltransferase activities

A. Chiapparino, F. De Giorgi, L. Scietti, S. Faravelli, T. Roscioli, F. Forneris

This study identifies key molecular interactions in LH3 that enable its dual glycosyltransferase activities and provides structural insights for inhibitor development.

bioRxiv · Apr 4, 2020 · PreprintBiochemistry