Author

F. Forneris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Bioengineering· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 3 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:structural biology· 2

Frequent Co-Authors

L. Scietti· 3 shared S. Faravelli· 3 shared A. Pinnola· 2 shared A. Canciani· 1 shared A. Chiapparino· 1 shared A. Mougel· 1 shared A.-B. Failloux· 1 shared B. Leclerc· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

L. Scietti

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Molecular Structure and Enzymatic Mechanism of the Human Collagen Hydroxylysine Galactosyltransferase GLT25D1/COLGALT1

M. De Marco, S. R. Rai, L. Scietti, D. Mattoteia, S. Liberi, A. Pinnola, F. Forneris

This study characterizes the molecular structure and enzymatic mechanism of GLT25D1/COLGALT, identifying its catalytic site and dimeric assembly as critical for collagen lysine modification.

bioRxiv · Jun 21, 2024Biochemistry

SARS-CoV-2 Spike Affinity and Dynamics Exclude the Strict Requirement of an Intermediate Host

M. Castelli, L. Scietti, N. Clementi, M. Cavallaro, S. Faravelli, A. Pinnola, E. Criscuolo, R. A. Diotti, M. Clementi, F. Forneris, N. Mancini

This study shows SARS-CoV-2 and RaTG13 spikes have similar ACE2 binding affinities, suggesting minimal species barriers, and highlights SARS-CoV-2's optimized dynamics for human ACE2 engagement.

bioRxiv · Aug 11, 2021 · PreprintMicrobiology

NT-mini, a recombinant tool for the study of Neurotrypsin functionality

A. Canciani, C. Capitanio, S. Stanga, S. Faravelli, P. Kienlen-Campard, F. Forneris

This paper develops NT-mini, a catalytically competent truncated form of Neurotrypsin, to study its functionality and interactions, revealing new insights into its heparin-binding domain and zinc-based modulation.

bioRxiv · Oct 1, 2020 · PreprintBiochemistry

Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent minimal MET receptor agonist.

G. de Nola, B. Leclerc, A. Mougel, S. Dezitter-Taront, C. Simonneau, F. Forneris, E. Adriaenssens, H. Drobecq, O. Melnyk, E. Gherardi, H. de Jonge, J. Vicogne

This study designs and characterizes K1K1, a minimal MET receptor agonist made from two kringle 1 domains of HGF/SF, showing stability and biological activity comparable to native HGF/SF in vitro and in a mouse liver disease model.

bioRxiv · Jul 20, 2020Bioengineering

A cooperative network of molecular "hot spots" highlights the complexity of LH3 collagen glycosyltransferase activities

A. Chiapparino, F. De Giorgi, L. Scietti, S. Faravelli, T. Roscioli, F. Forneris

This study identifies key molecular interactions in LH3 that enable its dual glycosyltransferase activities and provides structural insights for inhibitor development.

bioRxiv · Apr 4, 2020 · PreprintBiochemistry

Polymorphism analyses and protein modelling inform on functional specialization of Piwi clade genes in the arboviral vector Aedes albopictus

M. Marconcini, L. Hernandez, G. Iovino, V. Houe, F. Valerio, U. Palatini, E. Pischedda, J. E. Crawford, R. Carballar-Lejarazu, L. Ometto, F. Forneris, A.-B. Failloux, M. Bonizzoni

This study analyzes polymorphism and protein structure of Piwi clade genes in Aedes albopictus to identify functional specialization and antiviral roles.

bioRxiv · Jun 19, 2019Evolutionary Biology