MicrobiologybioRxivPreprint
Cytomegalovirus-induced inactivation of TSC2 disrupts the coupling of fatty acid biosynthesis to glucose availability resulting in a vulnerability to glucose limitation
M. H. Raymonda, I. Rodriguez-Sanchez, X. Schafer…·J. Munger
This paper shows that HCMV's UL38 protein inactivates TSC2, disrupting glucose-fatty acid biosynthesis coupling and making cells vulnerable to glucose limitation.
DOI 10.1101/2023.05.17.541212