Interferon epsilon restricts Zika virus infection in the female reproductive tract
C. Xu, A. Wang, L. Ebraham, L. Sullivan, C. Tasker, V. Pizutelli, J. Couret, C. Hernandez, P. Q. Deb, L. Fritzky, S. Subbian, N. Gao, Y. Lo, M. Salvatore, A. Rivera, , T. L. Chang
This study shows that IFNε protects against vaginal ZIKV infection in mice by maintaining epithelial integrity and is effective even without IFNAR1 signaling.
bioRxiv · Apr 6, 2023Immunology