Author

L. T. Chong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Bogetti· 1 shared A. J. DeGrave· 1 shared D. C. Favaro· 1 shared J. Closson· 1 shared K. H. Gardner· 1 shared L. P. Marcelino· 1 shared M. L. Silvestrini· 1 shared R. Solazzo· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperBiophysics

A. Bogetti

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2 papers

Recent·Most cited

BiochemistrybioRxivNov 3, 2023

Identification of Small Molecule Ligand Binding Sites On and In the ARNT PAS-B Domain

X. Xu, J. Closson, L. P. Marcelino…·K. H. Gardner

The paper identifies ligand-binding sites on and within the ARNT PAS-B domain using NMR, MD simulations, and ensemble docking, revealing distinct binding modes for three small molecules.

DOI 10.1016/j.jbc.2024.107606

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiophysicsbioRxivDec 21, 2020

The RED scheme: Rate-constant estimation from pre-steady state weighted ensemble simulations

A. J. DeGrave, A. Bogetti, L. T. Chong

The RED scheme improves rate-constant estimation from simulations by using event duration distributions, achieving up to 50% greater efficiency than existing methods.

DOI 10.1063/5.0041278

statistical model

𝕏 PostBluesky