ImmunologybioRxivPreprint
Spatial and temporal plasticity of neoantigen-specific T-cell responses bases on characteristics associated to antigen and TCR
E. Braeunlein, G. Lupoli, E. T. Abalrous…·A. M. Krackhardt
The paper characterizes neoantigen-specific T-cell receptors in a melanoma patient, showing that low-avidity TCRs can provide effective anti-tumor responses and persist long-term in blood and tissues.
DOI 10.1101/2021.02.02.428777