Author

L. Witte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Cho· 2 shared C. Gaebler· 2 shared F. Muecksch· 2 shared F. Schmidt· 2 shared M. C. Nussenzweig· 2 shared M. Caskey· 2 shared P. D. Bieniasz· 2 shared R. Raspe· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Cho

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape

L. Witte, V. Baharani, F. Schmidt, Z. Wang, A. Cho, R. Raspe, M. C. Guzman-Cardozo, F. Muecksch, C. Gaebler, M. Caskey, M. C. Nussenzweig, T. Hatziioannou, P. D. Bieniasz

The paper shows that epistasis reduces the genetic barrier for SARS-CoV-2 variants to escape broadly neutralizing antibodies by enabling resistance through combinations of mutations.

bioRxiv · Aug 17, 2022Microbiology

Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection

Z. Wang, P. Zhou, F. Muecksch, A. Cho, T. B. Tanfous, M. Canis, L. Witte, B. Johnson, R. Raspe, F. Schmidt, E. Bednarski, J. DaSilva, V. Ramos, S. Zong, M. Turroja, , M. C. Nussenzweig

This study compares memory B cell responses after Delta and Omicron BA.1 breakthrough infections versus mRNA vaccine doses, finding that Delta infection boosts overall memory B cell potency and breadth, while Omicron infection only enhances strain-specific responses.

bioRxiv · Aug 11, 2022Immunology

Ykt6 membrane-to-cytosol cycling regulates exosomal Wnt secretion

K. Linnemannstöns, P. Karuna M, L. Witte, J. C. Kittel, A. Danieli, D. Müller, L. Nitsch, M. Honemann-Capito, F. Grawe, A. Wodarz, J. C. Gross

This study shows that Ykt6 phosphorylation regulates exosomal Wnt secretion by controlling its membrane-to-cytosol cycling during endosomal maturation.

bioRxiv · Dec 3, 2018 · PreprintCell Biology