Similar deamination activity but different phenotypic outcomes induced by APOBEC3 enzymes in breast epithelial cells
M. Granadillo Rodriguez, L. Wong, L. Chelico
This study compares the mutagenic effects of APOBEC3A, APOBEC3B, and APOBEC3H in breast cells, finding similar DNA damage but distinct cancer-related phenotypes.
bioRxiv · Mar 29, 2023 · PreprintCancer Biology