Author

L. Zerad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Cherian· 1 shared D. Vukic· 1 shared J. Melicherova· 1 shared J. Prochazka· 1 shared K. Sinigaglia· 1 shared L. P. Keegan· 1 shared M. A. O'Connell· 1 shared N. Bondurand· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Cherian

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1 paper

Recent·Most cited

Aberrant activation of the innate immune sensor PKR by self dsRNA is prevented by direct interaction with ADAR1

K. Sinigaglia, A. Cherian, D. Vukic, J. Melicherova, P. Linhartova, Q. Du, L. Zerad, S. Stejskal, R. Malik, J. Prochazka, N. Bondurand, R. Sedlacek, M. A. O'Connell, L. P. Keegan

The paper identifies PKR as a second dsRNA sensor aberrantly activated in Adar mutant mice and shows ADAR1 directly inhibits PKR through dsRNA-binding.

bioRxiv · Aug 29, 2023 · PreprintImmunology