PGRMC1 phosphorylation and cell plasticity 2: genomic integrity and CpG methylation
B. M. Thejer, P. P. Adhikary, S. L. Teakel, J. Fang, P. A. Weston, S. Gurusinghe, A. G. Anwer, M. Gosnell, J. A. Jazayeri, M. Ludescher, L.-A. Gray, M. Pawlak, R. H. Wallace, S. D. Pant, M. Wong, , M. A. Cahill
This study shows that PGRMC1 phosphorylation mutants alter genomic stability, CpG methylation, and cell metabolism, suggesting a role in cellular plasticity and tissue differentiation.
bioRxiv · Sep 18, 2019Cell Biology