GeneticsG3 Genes Genomes GeneticsPeer-reviewed
A comprehensive in vivo screen of yeast farnesyltransferase activity reveals broad reactivity across a majority of CXXX sequences
June H Kim, Emily R. Hildebrandt, Anushka Sarkar…·Walter K. Schmidt
The paper evaluates all possible CXXX sequences as farnesyltransferase targets in yeast using a reporter system, revealing expanded specificity beyond the canonical CaaX motif.
13 citations