Author

Emily R. Hildebrandt

University of GeorgiaORCID 0009-0003-5053-4377Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anushka SarkariD· 3 shared June H Kim· 3 shared Walter K. SchmidtiD· 3 shared Emily T. Mai· 1 shared Khushi V. Patel· 1 shared La Ryel A Waldon· 1 shared Natarajan KannaniD· 1 shared Rajani RavishankariD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersGenetics

Anushka SarkarORCID

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3 papers

Recent·Most cited

BiochemistryDisease Models & MechanismsPeer-reviewedMay 1, 2024

A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences

Emily R. Hildebrandt, Anushka Sarkar, Rajani Ravishankar…·Walter K. Schmidt

The paper develops humanized yeast strains expressing human prenyltransferases to study prenylation of diverse CaaX sequences from human and viral proteins.

2 citations

yeastproteomics

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GeneticsbioRxivPreprintMar 4, 2024

Comprehensive analysis of CXXX sequence space reveals that S. cerevisiae GGTase-I mainly relies on a2X substrate determinants

Anushka Sarkar, Emily R. Hildebrandt, Khushi V. Patel…·Walter K. Schmidt

The paper evaluates S. cerevisiae GGTase-I specificity across all CXXX sequences, finding that non-canonical motifs with non-polar a2 and hydrophobic terminal residues are preferred.

DOI 10.1101/2024.03.04.583369

yeastproteomics

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GeneticsG3 Genes Genomes GeneticsPeer-reviewedApr 29, 2023

A comprehensive in vivo screen of yeast farnesyltransferase activity reveals broad reactivity across a majority of CXXX sequences

June H Kim, Emily R. Hildebrandt, Anushka Sarkar…·Walter K. Schmidt

The paper evaluates all possible CXXX sequences as farnesyltransferase targets in yeast using a reporter system, revealing expanded specificity beyond the canonical CaaX motif.

13 citations

yeastexperimental assay

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