Lan Wang

Photoreceptor-derived FGF2 mediates a protective stress response without driving pathological retinal neovascularization in ischemic retinopathy

This study identifies rod photoreceptors as a source of FGF2 during ischemic retinopathy, showing it promotes photoreceptor survival without driving pathological neovascularization.

The circadian gene Dec2 promotes pancreatic cancer dormancy by regulating tumor cell antigen presentation to facilitate immune evasion

This study identifies Dec2 as a circadian gene that promotes pancreatic cancer dormancy by reducing MHC-I antigen presentation, enabling immune evasion.

Defining and rescuing pathomechanisms of myotubularin and autophagy disruption in a novel human cell model of Charcot-Marie-Tooth Type 4B3

This study creates a human cell model of CMT4B3 to show that motor neurons are most vulnerable to SBF1 mutations and that VPS34-IN1 can rescue cell death.

Covalent Leader Peptide Probes Enable Proteome-Level Mapping of RiPP Enzymes beyond Biosynthetic Gene Clusters

This study develops covalent leader peptide probes to identify RiPP enzymes outside biosynthetic gene clusters, revealing cross-cluster enzymatic interactions.

Does Unfairness Evoke Anger or Disgust? A Quantitative Neurofunctional Dissection Based on 25 Years of Neuroimaging

The paper uses neuroimaging data to dissect the neural differences between unfairness and moral emotions like anger and disgust, identifying distinct brain networks involved in each.

Fear of missing out (FOMO) associates with reduced cortical thickness in core regions of the posterior default mode network and higher levels of problematic smartphone and social media use