Author

Larry Babb

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:variant effect prediction· 2 Assay:whole-exome sequencing· 2 Approach:benchmark study· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Ada HamoshiD· 1 shared Adam L. Felsenfeld· 1 shared Adam W. HanseniD· 1 shared Alicia B. ByrneiD· 1 shared Anne O’Donnell‐LuriaiD· 1 shared Arif O. HarmanciiD· 1 shared Arthur L. BeaudetiD· 1 shared Beryl B. CummingsiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Ada HamoshORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 18, 2026

Calibration of in-frame indel variant effect predictors for clinical variant classification

Haneen Abderrazzaq, Mugdha Singh, Larry Babb…·ClinGen Variant Classification Working Group

This study calibrates in-frame indel variant effect predictors for clinical classification, showing they reach multiple evidence levels but perform worse than missense predictors.

2 citations

humanwhole-exome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicineGenetics in MedicinePeer-reviewedFeb 8, 2022

Centers for Mendelian Genomics: A decade of facilitating gene discovery

Samantha M. Baxter, Jennifer Ellen Posey, Nicole J. Lake…·Kurt N. Hetrick

The paper describes the role of the Centers for Mendelian Genomics in advancing gene discovery through data sharing, collaboration, and resource development over the past decade.

72 citations

humanwhole-exome sequencing

𝕏 PostBluesky