NeurosciencebioRxiv
Heterozygous mutation to Chd8 causes macrocephaly and widespread alteration of neurodevelopmental transcriptional networks in mouse
Andrea L Gompers, Linda Su-Feher, Jacob Ellegood…·Alex S Nord
This study shows that heterozygous Chd8 mutation in mice causes macrocephaly and widespread transcriptional changes in neurodevelopmental networks, similar to human CHD8 mutations.
DOI 10.1038/nn.4592