Author

Leslie C. Lopez

Broad Institute

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Microbiology· 1

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Abigail L. MansoniD· 1 shared Alexis Jaramillo CartagenaiD· 1 shared Ashlee M. EarliD· 1 shared Jennifer SuiD· 1 shared Jonathan D. Chen· 1 shared Joshua T. SmithiD· 1 shared K. L. TayloriD· 1 shared Roby P. BhattacharyyaiD· 1 shared

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1 shared paperMicrobiology

Abigail L. MansonORCID

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1 paper

Recent·Most cited

MicrobiologymBioPeer-reviewedOct 2, 2025

The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in the Enterobacterales

Alexis Jaramillo Cartagena, K. L. Taylor, Leslie C. Lopez…·Roby P. Bhattacharyya

This study shows that carbapenemase-producing CRE exhibit an inoculum effect, which can mislead susceptibility testing and highlights the need for improved detection methods.

12 citations

humanbulk RNA-seq

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