GeneticsAging CellPeer-reviewed
Clonal expansion of mitochondrial DNA deletions is a private mechanism of ageing in long-lived animals
Lakshmi Narayanan Lakshmanan, Zhuangli Yee, Li Fang Ng…·Jan Gruber
The paper identifies mtDNA deletions in ageing nematodes and finds they are rare, not age-dependent, and not clonally expanded, suggesting they are not a major driver of ageing in short-lived species.
43 citations