Author

Li Jiang

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alicia-Christina Baumgartner· 1 shared Andrey KorshunoviD· 1 shared Andrezza NascimentoiD· 1 shared Bernhard EnglingeriD· 1 shared Bing HouiD· 1 shared Bing ReniD· 1 shared Carlos Alberto Oliveira de BiagiiD· 1 shared Chen WangiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alicia-Christina Baumgartner

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell multidimensional profiling of tumor cell heterogeneity in supratentorial ependymomas

Daeun Jeong, Sara G. Danielli, Kendra K. Maaß, David R. Ghasemi, Svenja Kristin Tetzlaff, Ekin Reyhan, Li Jiang, Shashank Katiyar, Julia K. Sundheimer, Costanza Lo Cascio, Sina Neyazi, Carlos Alberto Oliveira de Biagi, Elsa Couvillon, Sophia Castellani, Maria F. Pazyra‐Murphy, , Mariella G. Filbin

This study integrates single-cell and spatial transcriptomics with live-cell imaging to characterize tumor heterogeneity in supratentorial ependymomas, revealing distinct progenitor-like states and spatial organization patterns.

Nature · Mar 11, 2026Peer-reviewedCancer Biology

Tryptophan Chemistry Driven by a Widespread Cytochrome P422 Enzyme Family

Wencheng Ma, Qian Wang, Qingyu Yang, Zhaojie Teng, Xiao Han, Moli Sang, Qiuyu Li, Ruili Wang, Peiyuan Feng, Jingyi Zhong, Yan Zhang, Yifeng Wei, Li Jiang, Frederick Peter Guengerich, Wei Zhang

The paper identifies a widespread cytochrome P422 enzyme family that performs four novel tryptophan transformations, revealing new enzymatic capabilities and introducing a computational tool for HBP discovery.

bioRxiv · Dec 13, 2025 · PreprintBiochemistry

An Array of 60,000 Antibodies for Proteome-Scale Antibody Generation and Target Discovery

Zhaohui Wang, Yang Li, Bing Hou, Mira I. Pronobis, Mingqiao Wang, Yuemeng Wang, Guangcun Cheng, Zhe Zhang, Yiqiang Wang, Yanfang Tang, Xuefan Xu, Rong Pan, 林飞, Nan Wang, Ziqing Chen, , Xun Meng

The paper develops PETAL, a library of 62,208 mAbs against 15,199 peptides, enabling proteome-scale antibody generation and target discovery across species.

Science Advances · Mar 11, 2020Peer-reviewedSystems Biology