Sara G. Danielli

This study integrates single-cell and spatial transcriptomics with live-cell imaging to characterize tumor heterogeneity in supratentorial ependymomas, revealing distinct progenitor-like states and spatial organization patterns.

This study develops L1CAM-CAR T cells that effectively target rhabdomyosarcoma despite low antigen density, showing improved efficacy and safety compared to existing CARs.

This study identifies therapy-resistant and tumor-acquired cell states in pediatric rhabdomyosarcoma using single-cell RNA sequencing.