Cell BiologybioRxivPreprint
APOE4 and INPP5D converge on membrane mechanics to regulate endocytosis in human astrocytes
Artur S. Gevorgyan, Lila M Gordon, Christian A. Combs…·Priyanka S. Narayan
This study shows APOE4 impairs endocytosis in astrocytes by altering membrane mechanics, and INPP5D restores this process by promoting clathrin curvature and maturation.
DOI 10.64898/2026.05.22.726347