NeurosciencebioRxiv
Divergent modulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 shapes dopaminergic cell activity and socio-emotional behavior
Tzanoulinou S., S. Astori, Laura Clara Grandi…·A. Vassalli
This study investigates the distinct roles of OX1R and OX2R in modulating dopaminergic neuron activity and socio-emotional behaviors in mice, revealing differential impacts on anxiety, hyperactivity, and learning.
DOI 10.1016/j.biopsych.2026.05.022