Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions
Daniel Butler, Christopher Mozsary, Cem Meydan, Jonathan Foox, Joel A. Rosiene, Alon Shaiber, David Danko, Ebrahim Afshinnekoo, Matthew J. MacKay, Fritz Joachim Sedlazeck, Nikolay A. Ivanov, Maria A. Sierra, Diana Pohle, Michael Zietz, Undina Gisladottir, , Christopher E. Mason
This study uses rapid diagnostics and metatranscriptomics to analyze SARS-CoV-2 infection, revealing viral evolution, host responses, and drug interactions in NYC samples.
Nature Communications · Mar 12, 2021Peer-reviewedMolecular Biology