BioengineeringScience AdvancesPeer-reviewed
Modeling Mechanical Activation of Macrophages During Pulmonary Fibrogenesis for Targeted Anti-Fibrosis Therapy
Ying Dong Xu, Linxuan Ying, Jennifer K. Lang…·Ruogang Zhao
This study models mechanical activation of macrophages in fibrotic lung tissue and shows pirfenidone inhibits this activation, offering a new mechanism for anti-fibrosis therapy.
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