ImmunologybioRxivPreprint
Clarifying the priming requirement and activator specificity for the NLRP3 inflammasome in human keratinocytes in vitro
Pritisha Rozario, Ying Shiang Lim, Shirley Suet Lee Ding…·Franklin L. Zhong
This study investigates NLRP3 inflammasome activation in human keratinocytes, showing it is induced by IFN-gamma but not LPS, and that specific activators like Hla target NLRP3 while nigericin activates both NLRP1 and NLRP3.
3 citations