Cell BiologybioRxivPreprint
Loss of FXR1 and FXR2 promotes accumulation of TDP-43 in aging-related stress granules
Sonja Menge, Lorena Decker, Karin M. Danzer…·Axel Freischmidt
The paper shows that loss of FXR1 and FXR2 leads to TDP-43 accumulation in stress granules, linking FXP family reduction to neurodegenerative pathology.
DOI 10.1101/2025.10.27.684798