BioengineeringScience AdvancesPeer-reviewed
Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo
Tianzheng Ye, Azmain Alamgir, Cara M. Robertus…·Matthew P. DeLisa
This paper develops programmable protein degraders (uAbs) that selectively knock down pathogenic β-catenin in vitro and in vivo, reducing tumor cell survival and proliferation.