BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
EPOP and MTF2 Activate PRC2 Activity through DNA-sequence specificity
Jeffrey Granat, Sanxiong Liu, Luis Popoca…·Danny Reinberg
This study shows EPOP and MTF2 enhance PRC2's histone methyltransferase activity through DNA-sequence specific binding, promoting H3K27me3 deposition in collaboration with JARID2.
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