Author

Lute Douglas

Rochester Institute of Technology

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alaa A. AbdelmageediD· 1 shared Jack SmerczynskiiD· 1 shared Matthew C. MorrisiD· 1 shared Maureen C. FerraniD· 1 shared Stephen DewhurstiD· 1 shared Tori L. RusselliD· 1 shared

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2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Alaa A. AbdelmageedORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 23, 2025

Constitutive NF-kB Activation is Amplified by VSV in Aggressive PC3 Prostate Cancer Cells that Resist Viral Oncolysis

Alaa A. Abdelmageed, Jack Smerczynski, Lute Douglas…·Maureen C. Ferran

This study shows that PC3 prostate cancer cells resist VSV oncolysis due to constitutive NF-kB activation, which is amplified by VSV infection through I{kappa}B--independent mechanisms.

DOI 10.1101/2025.09.23.678061

humanbulk RNA-seq

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