Author

M. A. Lewinsohn

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Cancer Biology· 1

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Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

A. F. Feder· 1 shared N. F. Müller· 1 shared T. Bedford· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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1 shared paperCancer Biology

A. F. Feder

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintAug 5, 2022

State-dependent evolutionary models reveal modes of solid tumor growth

M. A. Lewinsohn, T. Bedford, N. F. Müller, A. F. Feder

This paper introduces a Bayesian state-dependent evolutionary model to infer spatially varying cell division rates in tumors using multi-region sequencing data, finding peripheral cells divide 3-6x faster than central cells.

DOI 10.1101/2022.08.05.502978

humanbulk RNA-seq

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