MyD88-Dependent Signaling Drives Toll-Like Receptor-Induced Trained Immunity in Macrophages
A. M. Owen, L. Luan, K. R. Burelbach, M. A. McBride, C. L. Stothers, O. A. Boykin, K. Sivanesam, J. F. Schaedel, T. K. Patil, J. Wang, A. Hernandez, N. K. Patil, E. R. Sherwood, J. K. Bohannon
This study shows that MyD88-dependent signaling is critical for TLR-mediated trained immunity in macrophages, as demonstrated through experiments in mice and human cells.
bioRxiv · Aug 23, 2022Immunology