Author

L. Luan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. Zhang· 2 shared X. Liu· 2 shared A. Hernandez· 1 shared A. M. Owen· 1 shared C. L. Stothers· 1 shared D. Jiang· 1 shared D. Liang· 1 shared D. Wang· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. Zhang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Neuroprotective Mechanism of Ribisin A on H 2 O 2 -induced PC12 cell injury model

X. Zhang, M. Bao, J. Zhang, L. Zhu, D. Wang, X. Liu, L. Xu, L. Luan, Y. Liu, Y. Liu

This study investigates how Ribisin A protects PC12 cells from H2O2-induced injury by enhancing antioxidant activity, reducing inflammation, and modulating the ERK/CREB signaling pathway.

bioRxiv · Sep 27, 2023Pharmacology & Toxicology

Imaging interorganelle phospholipid transport by extended synaptotagmins using bioorthogonally tagged lipids

D. Liang, L. Luan, J. M. Baskin

The paper develops a method to visualize phospholipid transport between the plasma membrane and ER using bioorthogonal chemistry and extended synaptotagmins.

bioRxiv · Feb 1, 2023 · PreprintCell Biology

MyD88-Dependent Signaling Drives Toll-Like Receptor-Induced Trained Immunity in Macrophages

A. M. Owen, L. Luan, K. R. Burelbach, M. A. McBride, C. L. Stothers, O. A. Boykin, K. Sivanesam, J. F. Schaedel, T. K. Patil, J. Wang, A. Hernandez, N. K. Patil, E. R. Sherwood, J. K. Bohannon

This study shows that MyD88-dependent signaling is critical for TLR-mediated trained immunity in macrophages, as demonstrated through experiments in mice and human cells.

bioRxiv · Aug 23, 2022Immunology

ATG9 vesicles comprise the seed membrane of mammalian autophagosomes

T. J. Olivas, Y. Wu, S. Yu, L. Luan, P. Choi, S. Nag, P. De Camilli, K. Gupta, T. J. Melia

This study identifies ATG9 vesicles as the seed membrane for mammalian autophagosomes, showing they integrate proteins like LC3-II and are diluted as autophagosomes expand.

bioRxiv · Aug 16, 2022 · PreprintCell Biology

A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-Cov-2 virus and Omicron variant through a unique binding mode

D. Zhao, L. Liu, X. Liu, J. Zhang, Y. Yin, L. Luan, D. Jiang, X. Yang, L. Li, H. Xiong, D. Xing, Q. Zheng, N. Xia, Y. Tao, S. Li, H. Huang

This paper reports a synthetic nanobody, C5G2, that neutralizes SARS-CoV-2 and Omicron variants with high potency through a unique binding mechanism.

bioRxiv · Apr 11, 2022 · PreprintBiochemistry