Cell BiologybioRxiv
Quantitative Comparison of Presenilin Protein Expression Reveals Greater Activity of PS2-gamma-Secretase.
M. K. Eccles, N. Main, M. Sabale…·G. Verdile
This study quantifies PS1 and PS2 protein expression levels and shows PS2-gamma-secretase has equal or greater activity than PS1-gamma-secretase in APP and Notch1 processing.
DOI 10.1096/fj.202300954rr