Author

N. Main

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. J. Morgan· 1 shared A. J. Potter· 1 shared A. Maczurek· 1 shared A. R. R. Forrest· 1 shared A. Terry· 1 shared B. J. Dwyer· 1 shared B. Roberts-Mok· 1 shared C. Jackaman· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. J. Morgan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Quantitative Comparison of Presenilin Protein Expression Reveals Greater Activity of PS2-gamma-Secretase.

M. K. Eccles, N. Main, M. Sabale, B. Roberts-Mok, M. Agostino, D. Groth, P. E. Fraser, G. Verdile

This study quantifies PS1 and PS2 protein expression levels and shows PS2-gamma-secretase has equal or greater activity than PS1-gamma-secretase in APP and Notch1 processing.

bioRxiv · May 9, 2023Cell Biology

Single Nucleus RNA Sequencing of Pre-Malignant Liver Reveals Disease-Associated Hepatocyte State with HCC Prognostic Potential

R. Carlessi, E. Denisenko, E. Boslem, J. Koehn-Gaone, N. Main, N. D. B. A. Bakar, G. D. Shirolkar, M. Jones, D. Poppe, B. J. Dwyer, C. Jackaman, M. C. Tjiam, R. Lister, M. Karin, J. A. Fallowfield, , J. E. E. Tirnitz-Parker

The paper uses snRNA-seq to identify a disease-associated hepatocyte state in pre-malignant livers that correlates with HCC risk in mice and humans.

bioRxiv · Mar 25, 2022Cancer Biology

The Role of CD147 in Leukocyte Aggregation in Liver Injury

N. Main, C. Yee, A. Terry, I. Stevanovski, A. Maczurek, A. J. Morgan, S. Calabro, A. J. Potter, T. L. Iemma, D. G. Bowen, G. Ahlenstiel, F. J. Warner, G. W. McCaughan, S. V. McLennan, N. A. Shackel

This study identifies CD147 as a mediator of leukocyte aggregation in liver injury, showing that blocking CD147 reduces aggregate formation and liver damage without affecting overall leukocyte numbers.

bioRxiv · Apr 6, 2019Immunology