Author

M. Ailion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cell Biology· 2 Ecology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:C. elegans· 5 Research Focus:development & morphogenesis· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

I. Topalidou· 3 shared J. Cattin-Ortola· 3 shared B. Hummer· 2 shared C. S. Asensio· 2 shared H. S. Malik· 2 shared L. Caro· 2 shared P. Lamelza· 2 shared A. Dosey· 1 shared

Activity by Year

2016-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCell Biology

I. Topalidou

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Author profile →

8 papers

Recent·Most cited

Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species

L. Caro, P. Raman, F. A. Steiner, M. Ailion, H. S. Malik

The paper identifies frequent gene duplications of centromeric proteins in Caenorhabditis species, showing short-term retention and subsequent degeneration.

bioRxiv · Mar 31, 2022Evolutionary Biology

Local adaptation and spatiotemporal patterns of genetic diversity revealed by repeated sampling of Caenorhabditis elegans across the Hawaiian Islands

T. A. Crombie, P. Battlay, R. E. Tanny, K. S. Evans, C. M. Buchanan, D. E. Cook, C. M. Dilks, L. A. Stinson, S. Zdraljevic, G. Zhang, N. M. Roberto, D. Lee, M. Ailion, K. A. Hodgins, E. C. Andersen

This study samples C. elegans across Hawaii over three years, sequenced their genomes, and found seven genetic groups and 18 regions linked to local adaptation.

bioRxiv · Oct 11, 2021Ecology

Hybridization promotes asexual reproduction in Caenorhabditis nematodes

P. Lamelza, J. M. Young, L. M. Noble, L. Caro, A. Isakharov, M. Palanisamy, M. V. Rockman, H. S. Malik, M. Ailion

This paper investigates how hybridization between two Caenorhabditis nematode species leads to asexual reproduction through altered meiosis and genome inheritance.

PLOS Genetics · Dec 16, 2019Peer-reviewedEvolutionary Biology

CCDC186 controls dense-core vesicle cargo sorting by exit

J. Cattin-Ortola, I. Topalidou, H.-T. Lau, B. Hummer, C. S. Asensio, S.-E. Ong, M. Ailion

This study identifies CCDC186 as a regulator of DCV cargo sorting by exit, showing its role in retaining mature DCV cargos and removing non-DCV cargos post-TGN.

bioRxiv · Nov 6, 2019 · PreprintCell Biology

EIPR1 controls dense-core vesicle cargo retention and EARP complex localization in insulinoma cells

I. Topalidou, J. Cattin-Ortola, B. Hummer, C. S. Asensio, M. Ailion

This study investigates the role of EIPR1 in insulinoma cells, showing it controls DCV cargo retention and EARP complex localization, with effects on insulin secretion and cargo accumulation.

bioRxiv · Nov 6, 2019Cell Biology

Pristionchus nematodes occur frequently in diverse rotting vegetal substrates and are not exclusively necromenic, while Panagrellus redivivoides is found specifically in rotting fruits

M.-A. Felix, M. Ailion, J.-C. Hsu, A. Richaud, J. Wang

The paper investigates the ecological niches of Pristionchus and Panagrellus nematodes, finding they feed on decomposing vegetal matter and are transported by various arthropods, challenging the notion that they are exclusively necromenic.

bioRxiv · May 18, 2018Ecology

The Dense-Core Vesicle Maturation Protein CCCP-1 Binds RAB-2 and Membranes through its C-terminal Domain

J. Cattin-Ortola, I. Topalidou, A. Dosey, A. J. Merz, M. Ailion

This study identifies the C-terminal domain of CCCP-1 as essential for its localization, RAB-2 binding, membrane interaction, and role in DCV biogenesis.

bioRxiv · May 29, 2017Biochemistry

Cytoplasmic-nuclear incompatibility between wild-isolates of Caenorhabditis nouraguensis

P. Lamelza, M. Ailion

The paper identifies a cytoplasmic-nuclear incompatibility causing hybrid lethality between two wild isolates of Caenorhabditis nouraguensis, suggesting mitochondrial dysfunction as a key factor in reproductive isolation.

bioRxiv · Oct 26, 2016Evolutionary Biology