STAT3 expression in dendritic cells protects mice from colitis by a gut microbiome-dependent mechanism
J. Liu, K. Szilagyi, M. Capitano, A. K. Iyer, J. He, M. Olson, J. Du, W. Van Der Pol, C. D. Morrow, B. Zhou, M. Kaplan, A. L. Dent, R. Brutkiewicz
This study shows that STAT3 deficiency in dendritic cells leads to colitis in mice, which is dependent on the gut microbiome.
bioRxiv · Jul 31, 2021 · PreprintImmunology