Treatment with commonly used antiretroviral drugs induces a type I/III interferon signature in the gut in the absence of HIV infection
S. M. Hughes, C. N. Levy, F. Calienes, J. D. Stekler, U. Pandey, L. Vojtech, A. R. Berard, K. Birse, L. Noel-Romas, B. Richardson, J. B. Golden, M. Cartwright, A. C. Collier, C. E. Stevens, M. E. Curlin, , F. Hladik
This study shows that oral TDF/FTC antiretroviral drugs induce a type I/III interferon signature in the gut without HIV infection, potentially affecting immune responses.
bioRxiv · Aug 3, 2020Immunology