Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state
M. Ciganda, J. Sotelo-Silveira, J. T. Smith, S. Shen, J. Qu, P. Smircich, L. K. Read
This study shows that DRBD18 in Trypanosoma brucei regulates translational efficiency of specific transcripts, maintaining the procyclic form by repressing procyclic-specific proteins and enhancing bloodstream/metacyclic-specific proteins.
bioRxiv · Feb 8, 2023Microbiology