M. D. Phan

Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks

The paper develops a model combining tumor-specific methylation atlas and cfDNA features to improve tissue-of-origin detection in low-depth cfDNA samples.

Dual thermal ecotypes co-exist within a nearly genetically-identical population of the unicellular marine cyanobacterium Synechococcus

The study identifies two thermal ecotypes within a nearly genetically identical Synechococcus population, showing functional diversity in temperature adaptation.