Author

M. De

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:Xenopus· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

K. Toth· 2 shared R. C. Wade· 2 shared A. M. Manicone· 1 shared E. A. Hemann· 1 shared G. Mueller· 1 shared K. B. Hisert· 1 shared M. A. Oeztuerk· 1 shared M. E. Long· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

K. Toth

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MEK1/2 inhibition decreases pro-inflammatory responses in macrophages from people with cystic fibrosis and mitigates severity of illness in experimental murine methicillin-resistant Staphylococcus aureus infection

M. De, K. B. Hisert, W. C. Liles, A. M. Manicone, E. A. Hemann, M. E. Long

This study shows MEK1/2 inhibitors reduce inflammation in CF macrophages and improve outcomes in MRSA-infected mice without affecting pathogen clearance.

bioRxiv · Jan 22, 2023 · PreprintImmunology

Robustness of trinucleosome compaction to A-tract mediated linker histone orientation

M. De, M. Wuertz, G. Mueller, K. Toth, R. C. Wade

This study investigates whether A-tract mediated linker histone orientation affects trinucleosome compaction and stability, finding no significant differences in compaction or stability between DNA sequences with different A-tract positions.

bioRxiv · Aug 13, 2021 · PreprintBiophysics

DNA-sequence dependent positioning of the linker histone in a nucleosome: a single-pair FRET study

M. De, M. A. Oeztuerk, S. Isbaner, K. Toth, R. C. Wade

This paper uses single-pair FRET to show that the linker histone H1.0b binds on-dyad to A-tract DNA via minor groove recognition, revealing a new mechanism for AT-rich DNA binding.

bioRxiv · Dec 7, 2020Biophysics