ImmunologybioRxivPreprint
MEK1/2 inhibition decreases pro-inflammatory responses in macrophages from people with cystic fibrosis and mitigates severity of illness in experimental murine methicillin-resistant Staphylococcus aureus infection
M. De, K. B. Hisert, W. C. Liles…·M. E. Long
This study shows MEK1/2 inhibitors reduce inflammation in CF macrophages and improve outcomes in MRSA-infected mice without affecting pathogen clearance.
DOI 10.1101/2023.01.22.525092