Author

M. Dermit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

F. K. Mardakheh· 3 shared M. Dodel· 3 shared J. Ule· 2 shared M. S. Azman· 2 shared F. C. Y. Lee· 1 shared F. Capraro· 1 shared G. Guiducci· 1 shared H. Schwenzer· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

F. K. Mardakheh

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3 papers

Recent·Most cited

TREX reveals proteins that bind to specific RNA regions in living cells

M. Dodel, G. Guiducci, M. Dermit, S. Krishnamurthy, L. Stojic, F. K. Mardakheh

TREX identifies RNA-binding proteins interacting with specific RNA regions in living cells, revealing novel interactions in 45S rRNA and U1 snRNA.

bioRxiv · Jun 30, 2023Cell Biology

An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene

M. S. Azman, M. Dodel, F. Capraro, R. Faraway, M. Dermit, W. Fan, J. Ule, F. K. Mardakheh

This study identifies Nucleolin as a key mediator of RAS-driven ribosome biogenesis and tumorigenesis through enhanced RNA-binding activity.

bioRxiv · Dec 16, 2021Cancer Biology

Subcellular mRNA localization regulates ribosome biogenesis in migrating cells

M. Dermit, M. Dodel, F. C. Y. Lee, M. S. Azman, H. Schwenzer, J. L. Jones, S. P. Blagden, J. Ule, F. K. Mardakheh

The paper shows that subcellular localization of RP-mRNAs via LARP6 enhances ribosome biogenesis during cell migration and supports cancer progression through EMT.

bioRxiv · Dec 2, 2019Cell Biology